The title of this editorial is the same given to the main document to be discussed, two months from now, at the Earth Summit 2012, the so-called Rio+20, in allusion to the 20th anniversary of the United Nations Conference on Environment and Development, also known as RIO-92.
The 1992 Summit, with its 27 principles, has been the most influential one because, beyond the environment itself, it placed human beings as the focus for the sustainable development, bringing, thus, for the discussion, issues such as hunger, diseases, disarmament, racial prejudice and genocide.
Structure
and Peroxidase Activity of Ferric Streptomyces clavuligerus orf10-encoded
Protein P450CLA: UV-Visible, CD, MCD and EPR Spectroscopic Characterization
Leandro
S. Goto, Carlos O. Hokka, José F. Lima, Tatiana Prieto, Ana Paula
U. Araújo, Iseli L. Nantes and Otaciro R. Nascimento
Soret bands of two states of recombinant
orf10-encoded P450-camphor like protein (P450CLA) of Streptomyces
clavuligerus expressed in Escherichia coli Rosetta: the resting
form (light gray) and the finger print of this hemeprotein characterized
by Soret band peaking at 450 nm for the ferrous-CO complex (pink). Cytochrome
P450 CLA is involved in the clavulanic acid biosynthetic pathway (color
structure at right side) able to inhibit β-lactamase of penicillin-resistant
bacteria. See details in the Article Structure and Peroxidase Activity
of Ferric Streptomyces clavuligerus orf10-encoded Protein P450CLA:
UV-Visible, CD, MCD and EPR Spectroscopic Characterization by Goto
et al. on page 913
Dialkylphosphorylhydrazones
as Potent Tyrosinase Inhibitors
Janaína M. R. Caixeiro, Vinicius T. Gonçalves, Márcia
C. C. de Oliveira, Carlos M. R. Sant’Anna,
Victor M. Rumjanek and João B. N. DaCosta
J.
Braz. Chem. Soc.2012,23, 804.
The
inhibition of the enzyme tyrosinase by some new organophosphorus compounds
was investigated with the aim of developing potential drugs useful for
the treatment of various skin disorders. Some compounds were found to
be more active than the commercial ascorbic acid
Effect
of Calcium Phosphate Coating on Polyamide Substrate for Biomaterial
Applications
Lucimara C. Bandeira, Kátia J. Ciuffi, Paulo S. Calefi, Eduardo
J. Nassar, Jorge V. L. Silva, Marcelo Oliveira, Izaque A. Maia, Isabel
M. Salvado and Maria Helena V. Fernandes
J.
Braz. Chem. Soc.2012, 23, 810.
Sol-gel
process used to prepare calcium coating as bioactive materials
Molecular
Identification and Phylogenetic Analysis of Egletes viscosa
(L.) Less.,
a Traditional Medicinal Plant from Northeastern Brazil
José M. M. Batista, Davi C. Torres, Daniel M. de M. Jorge, Carlos
E. A. Soares, Walderly M. Bezerra, Edilberto R. Silveira and Thalles
B. Grangeiro
J.
Braz. Chem. Soc.2012, 23, 818.
There
are two chemotypes of "macela" (Egletes viscosa (L.)
Less.), whose essential oils are characterized by the presence of trans-pinocarveyl
acetate (chemotype A) or cis-isopinocarveyl acetate (chemotype
B). Analysis of ITS/5.8S DNA sequences provides an effective and accurate
strategy for identifying the chemotypes from E. viscosa
Knoevenagel
Condensation of Aromatic Aldehydes with Ethyl 4-Chloro-3-oxobutanoate
in Ionic Liquids
Bruno R. S. de Paula, Dávila S. Zampieri, Julio Zukerman-Schpector,
Edward R. T. Tiekink,
José Augusto R. Rodrigues and Paulo J. S. Moran
J.
Braz. Chem. Soc.2012, 23, 825.
Knoevenagel
condensations of aromatic aldehydes with ethyl 4-chloro-3-oxobutanoate
were carried out in ionic liquids to give ethyl (E)/(Z)-2-chloroacetyl-3-arylpropenoates.
The ionic liquid [bmim(NTf2)] was reused
up to 4 times without loss in product yields, and an unequivocal methodology
of (E)/(Z)-structural analysis by 13C
NMR (nuclear magnetic resonance) is presented
Electrooxidation
of Ethanol on Pt and PtRu Surfaces Investigated by ATR Surface-Enhanced
Infrared Absorption Spectroscopy
Márcio F. Silva, Bruno C. Batista, Emerson Boscheto, Hamilton
Varela and Giuseppe A. Camara
J.
Braz. Chem. Soc.2012, 23, 831.
ATR-SEIRAS
experiments performed on Pt and PtRu electrodeposits show that CO is
formed at low potentials (~ 0.1 V) on both surfaces and remains adsorbed,
blocking surface sites and thus inhibiting ethanol oxidation. Kinetic
modeling suggests that CO adsorbed layer is not influenced by the presence
of Ru, whilst its oxidation is clearly favored in the presence of this
metal
Evaluation
of Metal Ions in Rice Samples: Extraction and Direct Determination
by ICP OES
Andrea Oliveira, Nivaldo Baccan and Solange Cadore
J.
Braz. Chem. Soc.2012, 23, 838.
The
extraction of metal ions present in rice samples with ammoniacal solution
of EDTA (pH 10) as extracting agent allowed the determination of P,
K, Mg, Ca, Zn, Mn, Cu and Mo in rice samples of type "integral",
"agulhinha" and "parboiled"
Assessment
of Inorganic Contaminants in Golden Mussel (Limnoperna fortunei)
in Southern Brazil
Éderson R. Pereira, Bruno M. Soares, João P. Vieira, Ana
C. G. Mai, Rochele S. Picoloto, Edson I. Muller, Erico M. M. Flores
and Fábio A. Duarte
J.
Braz. Chem. Soc.2012, 23, 846.
Bivalves have been widely used
as sentinel organisms for environmental monitoring of trace and major
element concentration in aquatic ecosystems. The simultaneous characterization
of this biomarker in different locations can provide information on
the pollution status in the region
Synthesis,
Urease Inhibition, Antioxidant and Antibacterial Studies of Some
4-Amino-5-aryl-3H-1,2,4-triazole-3-thiones and their 3,6-Disubstituted
1,2,4-Triazolo[3,4-b]1,3,4-thiadiazole Derivatives
Muhammad Hanif, Muhammad Saleem, Muhammad Tahir Hussain, Nasim Hasan
Rama, Sumera Zaib, Muhammad Adil M. Aslam, Peter G. Jones and Jamshed
Iqbal
J.
Braz. Chem. Soc.2012, 23, 854.
A
new series of 4-amino-5-aryl-3H-1,2,4-triazole-3-thiones was
condensed with different substituted aromatic acids to yield 3,6-disubstituted-1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles.
The synthesized compounds were screened for their urease inhibition,
antioxidant and antibacterial activities. Some compounds showed excellent
urease inhibition activities more than the standard drug
Estimating
Cocaine Consumption in the Brazilian Federal District (FD) by Sewage
Analysis
Adriano O. Maldaner, Luciana L. Schmidt, Marco A. F. Locatelli, Wilson
F. Jardim, Fernando F. Sodré, Fernanda V. Almeida, Carlos Eduardo
B. Pereira and Cristiano M. Silva
J.
Braz. Chem. Soc.2012, 23, 861.
The
consumption of cocaine in the Brazilian Federal District, via sewage
analysis, was estimated in 1.0 ton year-1. Sampling at different wastewater
treatment plants allowed the detection of areas with higher consumption
Support
Effect on Carbon Nanotube Growth by Methane Chemical Vapor Deposition
on Cobalt Catalysts
Hugo
A. Oliveira, Dante F. Franceschini and Fabio B. Passos
J.
Braz. Chem. Soc.2012, 23, 868.
The
support influences the activity and selectivity of cobalt catalysts
on carbon nanotube production. Co/Al2O3 showed the highest total carbon
yield and the Co/TiO2 showed the highest selectivity (80%) towards single
walled carbon nanotube formation
Synthesis
and Thermal Behavior of New Liquid Crystals Arylaldoxime Esters
Aline Tavares, Bárbara C. Arruda, Elvis S. Boes, Valter Stefani,
Hubert K. Stassen,
Leandra F. Campo, Ivan H. Bechtold and Aloir A. Merlo
J.
Braz. Chem. Soc.2012, 23, 880.
The
synthesis of a series of unstable fluorescent liquid-crystalline arylaldoxime
esters 6a-d and 8 is reported. The chemical stability
and liquid-crystalline as well as the photophysical properties of the
title compounds are described and showed to be dependent on the heating/cooling
cycles
Fatty
Acid Synthase Inhibitors Isolated from Punica granatum L.
He-Zhong Jiang, Qing-Yun Ma, Hui-Jin Fan, Wen-Juan Liang, Sheng-Zhuo
Huang, Hao-Fu Dai,
Peng-Cheng Wang, Xiao-Feng Ma and You-Xing Zhao
J.
Braz. Chem. Soc.2012, 23, 889.
Bioassay-guided
chemical investigation on the EtOH extract of the peels of Punica
granatum led to the isolation of 17 compounds including one new
oleanane-type triterpene named punicaone. Flavogallonic acid exhibited
the strong fatty acid synthase (FAS) inhibitory activity with IC50
10.3 µmol -1
Correlation
Between Electrochemical and Theoretical Studies on the Leishmanicidal
Activity of Twelve Morita-Baylis-Hillman Adducts
Yen G. de Paiva, Antônio A. de Souza, Claudio G. Lima-Junior,
Fábio P. L. Silva, Edilson B. A. Filho, Camila C. de Vasconcelos,
Fabiane C. de Abreu, Marília O. F. Goulart and Mário L.
A. A. Vasconcellos
J.
Braz. Chem. Soc.2012, 23, 894.
This
work presents electrochemical studies, in aprotic media, of twelve Morita-Baylis-Hillman
adducts (MBHA) with significant leishmanicidal activity, together with
conformational calculations. Ortho adducts present facilitated
reduction in comparison to the other isomers and higher leishmanicidal
activity. Molecular hardness (N) and atomic charges (QN)
values corroborate the obtained experimental data
Studies on the Chemical Behavior of 3-(Nitroacetyl)-1-ethyl-4-hydroxyquinolin-2(1H)-one
towards some Electrophilic and Nucleophilic Reagents
Magdy A. Ibrahim, Hany M. Hassanin, Yassin A. Gabr and Youssef A. Alnamer
J.
Braz. Chem. Soc.2012, 23, 905.
A
variety of heterocyclic systems linked 1-ethylquinolin-2(1H)-one,
were prepared from reaction of 3-(nitroacetyl)-1-ethyl-4-hydroxyquinolin-2(1H)-one
with some electrophilic and nucleophilic reagents
Structure
and Peroxidase Activity of Ferric Streptomyces clavuligerus orf10-encoded
Protein P450CLA: UV-Visible, CD, MCD and EPR Spectroscopic Characterization
Leandro S. Goto, Carlos O. Hokka, José F. Lima, Tatiana Prieto,
Ana Paula U. Araújo, Iseli L. Nantes and Otaciro R. Nascimento
J.
Braz. Chem. Soc.2012, 23, 913.
The
ferrous recombinant orf10-encoded P450-camphor like protein (the
P450CLA) of Streptomyces clavuligerus exhibits the fingerprint
red shift to 450 nm after complexation with CO and peroxidase activity
towards tert-butylhydroperoxide
Size-Segregated
Particulate Matter and Carboxylic Acids over Urban and Rural Sites
in Londrina City, Brazil
Adriana de M. Freitas, Leila D. Martins and Maria Cristina Solci
J.
Braz. Chem. Soc.2012, 23, 921.
The results indicated that primary sources
of vehicular emissions were the dominant source of carboxylic acids
in urban and rural PM2,5 in Londrina City. Moreover, backward trajectories
indicated transport of pollutants from São Paulo to Londrina
Reactivity
of Glycerol/Acetone Ketal (Solketal) and Glycerol/Formaldehyde Acetals
toward Acid-Catalyzed Hydrolysis
Leonardo P. Ozorio, Rafael Pianzolli, Maria Beatriz S. Mota and Claudio
J. A. Mota
J.
Braz. Chem. Soc.2012, 23, 931.
The
acid-catalyzed hydrolysis of the glycerol/acetone ketal (solketal) and
glycerol/ formaldehyde indicated that solketal was significantly more
reactive than glycerol/ formaldehyde acetals. DFT calculations of the
ketal and acetal isomers explain the experimental distribution
Determination
of Tetracycline in Environmental Water Samples at a Graphite-Polyurethane
Composite Electrode
Carolina M. F. Calixto, Priscila Cervini and Éder T. G. Cavalheiro
J.
Braz. Chem. Soc.2012, 23, 938.
In
the present work, a graphite-polyurethane composite electrode was used
for the determination of tetracycline, an antibiotic widely used in
animal and human antibacterial treatment. Once in environmental waters,
tetracycline can be a potential pollutant from veterinary/medical use
as well as in pharmaceutical industry wastes
Speciation
of Fe(II) and Fe(III) by using Dispersive Liquid-Liquid Microextraction
and Flame Atomic Absorption Spectrometry
Soleiman Bahar and Razieh Zakerian
J.
Braz. Chem. Soc.2012, 23, 944.
The
figure shows the efficiency of dispersive liquid-liquid microextraction
method for the extraction of iron ion with oxine ligand using different
extraction (CH3Cl, CCl4, CH2Cl2
and CS2) and dispersive (methanol, ethanol,
acetone, acetonitrile and THF) solvents
Effect
of Fluorination Treatment on Electrochemical Properties of M1Ni3.5Co0.6Mn0.4Al0.5
Hydrogen Storage Alloy
Hongxia Huang and Kelong Huang
J.
Braz. Chem. Soc.2012, 23, 951.
Fluorination
treatment improves the discharge capacity and cycle durability of M1Ni3.5Co0.6Mn0.4Al0.5
alloy, which is attributed to a relatively lower cell volume changes
during hydriding/dehydriding. Moreover, the electrochemical reaction
resistance of the alloy electrode decreases after the treatment
Multivariate
Treatment of LIBS Data of Prehistoric Paintings
Flávia de S. L. Borba, Juliana Cortez, Viviane K. Asfora, Celio
Pasquini, Maria Fernanda Pimentel, Anne-Marie Pessis and Helen J. Khoury
J.
Braz. Chem. Soc.2012, 23, 958.
Prehistoric
painting samples from Toca da Extrema II Archaeological Site (Piauí
State, Brazil) and Xique-Xique Archaeological Site (Rio Grande do Norte
State, Brazil). Score plot of PCA carried on the LIBS (laser-induced
breakdown spectroscopy) spectra set of Toca da Extrema II Archaeological
Site painting
O-Iodoxybenzoic
Acid in Water: Optimized Green Alternative for Multicomponent One-Pot
Synthesis of 2-Amino-3,5-dicarbonitrile-6-thiopyridines
Santosh Takale, Jaidas Patil, Vikas Padalkar, Rajaram Pisal and Atul
Chaskar
J.
Braz. Chem. Soc.2012, 23, 966.
Environmentally
benign and eco-friendly protocol has been developed for the synthesis
of 2-amino-3,5-dicarbonitrile-6-thio-pyridine from aldehyde, malononitrile
and thiophenol
Determination
of Phenol and o-Cresol in Soil Extracts by Flow Injection Analysis
with Spectrophotometric Detection
Rafael G. Dolatto, Iara Messerschmidt, Betânia F. Pereira, Carlos
A. P. Silveira and Gilberto Abate
J.
Braz. Chem. Soc.2012, 23, 970.
The
official spectrophotometric method (APHA) for quantification of total
phenol in water was adapted to flow injection analysis (FIA) for phenol
and o-cresol determinations in soil extracts. As shown in the
figure, a good agreement between the results was verified in a recovery
study, with similar limit of quantification and sampling rate, near
50 analyses per h
Cytotoxic
Sesquiterpene Lactones and other Constituents of Centaurea omphalotricha
El Hadj Kolli, Francisco León, Fadila Benayache, Sara Estévez,
José Quintana, Francisco Estévez, Ignacio Brouard, Jaime
Bermejo and Samir Benayache
J.
Braz. Chem. Soc.2012, 23, 977.
Phytochemical
study of the aerial parts of Centaurea omphalotricha Coss. &
Durieu ex Batt. et Trab., an Algerian endemic plant, afforded three
new sesquiterpene lactones together with twelve known compounds, some
of them display strong cytotoxic properties in human leukemia cells
